Text Appearing Before Image: que method of inserting aneedle into a vein which is not easily palpable or visible. Bymeans of a small round stiletto he had fashioned for the pur-pose, a window is made in the skin over the vein, the skin firstbeing pulled to one side, so that the stiletto will not injure thevein. This leaves a window twice the size of the needle directlyover the vein. With the vein well distended and often visiblethrough the hole, it is easy to slip the needle through the openingdirectly into the vessel. Concentrated Injections of Arsphenamine Some men of great eminence are utilizing salvarsan in theconcentrated method. Dr. E. L. Keyes, Jr., in his splendid bookon Urology observes, page 827, that the original technic callsfor the administration of 300 c. c. of fluid. At present the usualallowance is 10 c. c. of distilled water for every decigram of thedrug to be injected. The dose for the adult male is three orfour decigrams; for the adult woman, three decigrams; for theinfant, one centigram. . . . Text Appearing After Image: S £ § 3 -C o *j 4; > £ o fc .a c/j 0) & <jO 3 W P I—I oH -° H ; i) 0) P ■& s a la u O 3 *-» og-.E ■1/ TECHNIC OF ARSPHENAMINE ADMINISTRATION 57 The injection is made either by gravity or with a 30 c. c.piston syringe or by a syringe to which is attached a three-waystopcock and one rubber tube leading into the bottle containingthe salvarsan, while the other leads to the needle in the patientsarm. Whatever the method employed, it is essential that thesalvarsan be given slowly and that at least five and preferablyten minutes be taken for the injection of the 30 c. c. Therefore,the gravity method is the safest. The concentrated method of salvarsan introduction is doubt-less a safe one in the hands of so experienced and skillful anoperator as Dr. Keyes, but for the average medical man, partof whose time must necessarily be given to other lines of medicine,we feel that the concentrated method is unsafe. Dr. Keyestechnic is presented to show that the concentration of
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